siRNA/chemically modified siRNA synthesis

Biotools provide the latest siRNA synthesis technique. We provide chemically modified siRNA that can specifically bind to the target DNA, has longer effect and also increases the affection to 20%.Our siRNA can be easily delivered into animals, which can help your experiments.
 

 

siRNA

Chemically modified siRNA

in vitro stability

weak

strong

Reaction time

shorter, 1 week

Longer, 2 weeks

in vivo activity

weak

strong

Reproducibility

high

higher

 

                                                    *siRNA and Chemically-modified siRNA

siRNA

2OD / 4OD/8OD

in vivo siRNA

chemically-modified siRNA

 

 

*siRNA and Chemically-modified siRNA set - Guaranteed > 70% knock-down in mRNA level                                  

siRNA set

   3 x 2 OD negative control siRNA
   1 OD negative control siRNA
   1 OD FAM labeled negative control siRNA
   1 OD positive control siRNA 

Chemically-modified siRNA set